Everton were unable to secure a point against the Champions as Manchester City another win against the Toffees. Riyad Mahrez and Raheem Sterling were on target as the Citizens earn additional 3 points.
The defending champions started well and, after Ilkay Gundogan somehow hit the bar from point-blank range, they took a deserved lead thanks to another moment of genius from Kevin De Bruyne.
His trademark whipped cross from the right was nodded home by Gabriel Jesus, giving the Belgian his eighth assist of a stellar campaign.
That spelled trouble for Everton, whose boss Marco Silva was under pressure before kick-off after back-to-back league defeats, but they responded well and were soon level.